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Games like Project Chemistry | IndieDex

Project Chemistry
Games like Project Chemistry

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single-players with secrets you find without a guideor

Games like Project Chemistry

A compact ~6.5-hour chemistry sandbox and quest-mode sim where you trigger reactions and synthesize molecules, with a playful educational edge.

MOLEK-SYNTEZ
A single-player programming puzzle about automating molecule synthesis in a Romanian apartment, with a calm, cerebral mood and a compact campaign.
2019-11-19
- Science fiction
- Puzzle

Bird view / Isometric

Indie

Simulator

Sandbox

The Powder Toy cover art

The Powder Toy

An open-ended physics sandbox for tinkering with heat, pressure, gravity, and countless substance interactions, with a playful, chaotic tone and highly variable session lengths.

2024-06-14

Side view
Simulator
Sandbox

Alchemist Simulator cover art

Alchemist Simulator

A short casual alchemy sim focused on contract-driven progression, puzzle-like potion crafting, and lab upgrades, with reviewer feedback pointing to a few rough edges.

2020-10-23

Puzzle
Adventure
Indie
Simulator
Kids

Water Physics Simulation cover art

Water Physics Simulation

A relaxing 2D sandbox physics toy where you build and destroy ships, cars, and towns with water, bombs, and disasters.

2021-10-06

Indie
Side view
Simulator
Sandbox

Alchemy Unbound cover art

Alchemy Unbound

A free-to-play, open-ended drag-and-drop crafting sim where players experiment with endless combinations, with a median reviewer playtime of around two hours.

2024-07-04

Strategy
Indie
Simulator

Unreal Physics cover art

Unreal Physics

A free-to-play casual 3D physics sandbox with realistic demos and a short, well-received tinkering experience.

2024-03-24

Indie
Simulator
Sandbox

Covid Simulator cover art

Covid Simulator

A compact single-player sandbox simulation where you manage Covid mandates and roll dice to see how a workplace outbreak unfolds.

2022-01-25

Comedy
Survival
Indie
Simulator
Sandbox
Educational

Space Simulation Toolkit cover art

Space Simulation Toolkit

A GPU-powered physics sandbox for rewriting physics, building mechanisms, and experimenting with A-Life and evolution; reviewers find it addictive and log 30+ hours.

2020-06-05

Science fiction
Bird view / Isometric
Indie
Simulator
Sandbox

SpaceChem cover art

SpaceChem

A demanding chemistry-based puzzle game about building automated factory lines, with a programming-like logic curve and a stark space-lab setting.

2011-03-02

Science fiction
Puzzle
Strategy
Bird view / Isometric
Indie
Simulator

Cellchemist cover art

Cellchemist

A physics sandbox puzzle game with over 100 simulated cell types, offering roughly two hours of gentle experimentation and puzzle-solving.

2026-02-13

Puzzle
Simulator

Purplis Sandbox cover art

Purplis Sandbox

A 2D single-player sandbox where you freely build structures and mechanisms, with a physics-toy feel and a mixed reception.

2021-01-14

Indie
Side view
Simulator
Sandbox

Dead 4 Now: Bio-Weapon Simulator cover art

Dead 4 Now: Bio-Weapon Simulator

A compact strategy sim where you craft lethal bio-weapons and iterate through trial-and-error to achieve global annihilation.

2026-04-17

First person
Strategy
Bird view / Isometric
Indie
Simulator
Business