Skip to main content

No ads. Ever. Help keep it that way. →

Loading games like…

Loading the shelf…

About
News

Privacy Policy Terms of Service

© IndieDex. All rights reserved.

SearchFollowing Library Profile

Games like Microcosmum: survival of cells | IndieDex

Microcosmum: survival of cells
Games like Microcosmum: survival of cells

Games like Microcosmum: survival of cells

A casual action-strategy game about surviving as a single-celled organism in a microscopic world, with light RPG progression and a roughly 8-hour playtime.

Pathogenic
A cellular roguelike shooter where you evolve a parasite against the immune system in a vibrant procedurally generated micro-world, with optional shared-screen co-op and a median reviewer playtime around three hours.
2026-07-16
- Shooter
- Action

Bird view / Isometric

Indie

Simulator

Role-playing (RPG)

Ecosystem cover art

Ecosystem

A relaxed underwater sandbox about guiding creatures through an emergent evolution simulation, with a loose, experimental feel and dozens of hours of play.

2024-11-08

Strategy
Bird view / Isometric
Indie
Simulator
Sandbox

Strange Seed cover art

Strange Seed

A single-player action-adventure RPG where you evolve a blob by eating DNA, with fast, goofy creature-building and a reviewer median playtime around 11 hours.

2025-11-05

Action
Adventure
Third person
Indie
Role-playing (RPG)

Mitos.is: The Game cover art

Mitos.is: The Game

A casual cross-platform microscopic-cell PvP/co-op game about eating others to grow, with daily tournaments, guilds, and gear.

2015-07-29

Action
Strategy
Bird view / Isometric
Simulator
Real Time Strategy (RTS)

Osmos cover art

Osmos

A physics-based ambient puzzle about growing by absorbing motes, balancing movement against shrinking, with a calm and quietly tense mood.

2009-08-18

Puzzle
Strategy
Bird view / Isometric
Indie
Simulator
Arcade

Thrive cover art

Thrive

A single-player evolution sim set on an alien planet where you edit your species and compete for resources, offering a laid-back sandbox feel with roughly 10-18 hours of current Early Access content.

2021-11-26

Survival
Strategy
Bird view / Isometric
Indie
Simulator
Open world
Non-fiction
Educational

DO NOT FEED THE VIRUS cover art

DO NOT FEED THE VIRUS

A short, casual mouse-driven incremental sim about growing a biomass colony, with level-based twists, ~3.5 hours of playtime, and mixed reviews citing simplicity and save-file issues.

2026-05-14

Action
Strategy
Indie
Simulator
Arcade

Lifecraft cover art

Lifecraft

An early-access strategy simulation where you manage a single cell's biological functions and evolve it into a complex organism, earning very positive reviews for its deep, open-ended gameplay.

2024-04-16

Strategy
Simulator
Sandbox

Sparkle ZERO cover art

Sparkle ZERO

An indie action-sim about evolving an organism from zero through resource competition, with a strange X-ray microscopic look and a ~4-hour run time.

2016-03-14

Action
Bird view / Isometric
Indie
Simulator
Arcade

Sparkle 2 Evo cover art

Sparkle 2 Evo

A short casual abstract game about evolving an aquatic sparkle with touch controls, though some players report stability issues.

2013-10-24

Action
Indie
Simulator
Arcade
Kids

Drifter Star: Evolution cover art

Drifter Star: Evolution

A short, relaxing space-absorption game where you evolve from a rock to a galaxy by devouring matter, though reviewers find it repetitive and derivative.

2025-12-10

Adventure
Strategy
Indie

Germ Wars cover art

Germ Wars

A single-player action game where you fight germs as a white blood cell, with ramming and upgrade mechanics and mixed reviews.

2016-11-21

Action
Indie