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Games like Antidote to despair | IndieDex

Antidote to despair
Games like Antidote to despair

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single-players with secrets you find without a guideor

Games like Antidote to despair

A ~4-hour Parisian antidote shop simulation about crafting cures and deciding between two morally fraught characters.

Perfume Atelier
A cozy single-player fragrance-crafting sim where you blend essences, design bottles, sell to customers, and decorate your atelier in a short ~11–13 hour experience.
2026-02-07
- Strategy
- Indie

Simulator

Role-playing (RPG)

1998: The Toll Keeper Story cover art

1998: The Toll Keeper Story

A bleak yet compassionate narrative simulation about a pregnant toll keeper navigating moral choices in a country on the brink of collapse.

2025-10-28

Bird view / Isometric
Indie
Simulator

Over the Counter cover art

Over the Counter

A single-player strategy sim about pharmaceutical management, where RNG shapes each run and reviewers logged around 16 hours.

2022-02-12

Strategy
Simulator

Alchemist Simulator cover art

Alchemist Simulator

A short casual alchemy sim focused on contract-driven progression, puzzle-like potion crafting, and lab upgrades, with reviewer feedback pointing to a few rough edges.

2020-10-23

Puzzle
Adventure
Indie
Simulator
Kids

Anvil Saga cover art

Anvil Saga

A medieval blacksmith-shop management sim with RPG decision-making, a short story, and recurring bugs that have drawn mixed reviews.

2023-11-16

Indie
Side view
Simulator
Role-playing (RPG)
Historical

Trolley Problem, Inc. cover art

Trolley Problem, Inc.

A brief, darkly comedic moral-dilemma game where you choose between impossible outcomes and compare your decisions with other players.

2022-04-21

Comedy
Indie
Simulator
Drama

Machine Child cover art

Machine Child

A mixed-reviewed single-player nurturing sim about raising a daughter through heartwarming adventures and choices, with a short median playtime.

2026-04-07

Adventure
Simulator
Text

Coffee Noir - Business Detective Game cover art

Coffee Noir - Business Detective Game

A noir-flavored business management sim with a detective story set in Neo-London, roughly 6-9 hours of uneven but story-driven gameplay.

2021-09-30

First person
Strategy
Indie
Simulator
Turn-based strategy (TBS)
Role-playing (RPG)
Business
Educational
Auditory

Safe Haven Repair Station cover art

Safe Haven Repair Station

A cozy cyberpunk repair-sim RPG about restoring items and shaping a dying city through choices, playable in about an hour.

2026-07-08

The Book of Plagues cover art

The Book of Plagues

A darkly humorous plague-doctor sim where your potion crafting and moral choices decide the city's fate, playable in about seven hours.

2026-01-16

Comedy
Indie
Simulator

In Trusted Hands cover art

In Trusted Hands

A cozy, short narrative sim about running a workshop, balancing energy and stress while making story-shaping choices.

2026-05-07

First person
Adventure
Indie
Simulator

Prescribe and Pray cover art

Prescribe and Pray

A single-player medical simulation with dark comedy, where you diagnose absurd patients and make life-or-death prescription choices.

2026-02-06

Indie
Simulator